This is the cover from some sort of Marvel Ultimate universe crossover thing that I guess was the biggest seller in comicdom last month, according to Tom Spurgeon.
It’s always interesting to see what continuity differences they throw in when they do these alternate universe wheezes. In this instance, for example, the Thing looks scarier, Reed Richards has glasses, and Sue Richards appears to have replaced her breasts with grapefruits.
Change we can believe in, I guess.